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The C-terminus is amidated (-NH 2 ) in all peptides, whereas only novel dual amylin and calcitonin receptor agonist (DACRA) compounds have an N-terminus acetylation (Ac-) for enhanced stability

Rutledge notes that "Ozempic personality" bears little resemblance to what happened with rimonabant, a weight loss drug that was withdrawn from the European market after being linked to severe depression and suicides