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Oxidative stress is commonly discussed in the context of illness and physiologic strain in dogs, and antioxidant supplementation has been proposed as supportive care in those situations (Hagen DM, 2019)

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34 This results in a predominant type of nevus, or signature nevus. 36 A nevus that has different characteristics from other nevi in a given patient (the ugly duckling) should be regarded with particular suspicion

Biochim Biophys Acta 546:426435 Hamada A, Tanaka Y, Ishikawa T, Maruta T (2023) Chloroplast dehydroascorbate reductase and glutathione cooperatively determine the capacity for ascorbate accumulation under photooxidative stress conditions