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Ozempic is indicated for managing type 2 diabetes, preventing kidney failure or worsening kidney disease in patients with chronic kidney disease and type 2 diabetes, and lowering the risk of cardiovascular events in patients with or without diabetes

doi: 10.1248/bpb.28.1827

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To address the role of the activator candidate for glutaredoxin catalysis, we replaced Lys105 of ScGrx7 by site-directed mutagenesis