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A recent study demonstrated that amphiphile modification of G12D and G12R mutant KRAS (mKRAS) peptides (Amph-Peptides-2P) in combination with CpG oligonucleotide adjuvant (Amph-CpG-7909) enhanced the delivery of cancer vaccines to lymph nodes and promoted anti-tumor immune responses in pancreatic and colorectal cancer (38)

Fluoxetine treatment of prepubertal male rats uniformly diminishes sex hormone levels and, in a subpopulation of animals, negatively affects sperm quality