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In the United States, bacteriostatic water for injection is classified as a prescription-only product

10.14814/phy2.13182 Physiol Rep

Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration

The 2024 Pharmaceutics review documents clinical evidence that Centella reduces post-procedure erythema and accelerates wound healing, with one controlled study showing erythema after laser resurfacing resolved on day 7 in the Centella group versus day 28 in placebo [15]