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12, doi: Nunes EA, Colenso-Semple L, McKellar SR, Yau T, Ali MU, Fitzpatrick-Lewis D, Sherifali D, Gaudichon C, Tome D, Atherton PJ, Robles MC, Naranjo-Modad S, Braun M, Landi F, Phillips SM

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Hepatocyte injury triggered by ER stress, mitochondrial dysfunction, or xenobiotics produces ROS, mitochondrial DNA, and apoptotic bodies that activate Kupffer cells (KCs) and HSCs (HSCs)

Before docking, water molecules and non-protein structures were removed, and hydrogen atoms were added to the protein structure, with Gasteiger charges assigned for accurate docking