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Conceiving of the study, participated in its design, study supervision, obtained funding and helping to draft the manuscript

Interestingly, the activated fibroblast phenotype, which is more proliferative and pro-inflammatory, is particularly pronounced in OA patients with obesity [88,89,90], even in non-load bearing joints i.e

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Sasaki K, Doh-ura K, Wakisaka Y, Iwaki T (2002) Clusterin/apolipoprotein J is associated with cortical Lewy bodies: immunohistochemical study in cases with alpha-synucleinopathie