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Mechanistically, BPC157 has been associated with: Strong angiogenic activity: stimulation of VEGF/VEGFR2 signaling, increased endothelial cell proliferation, and enhanced vascular running (growth of new vessels toward injured areas)

/ * 1 : 1 -157 5 , Peptide BPC-157 for Injection, Apex Biopharma, 1 amp * 5 mg Apex Biopharma : ApBi-157 -500 5 100 2 365

Inflammatory bowel disease represents the most advanced clinical target, with at least one Phase II trial having examined a BPC-157-derivative compound (PL 14736) for ulcerative colitis, showing preliminary evidence of mucosal healing in human patients