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Mitochondrial-Nuclear Communication: Under conditions of metabolic stress or exercise, MOTS-c translocates to the nucleus, where it regulates the expression of nuclear genes associated with stress adaptation and homeostasis
Ninety healthy individuals were enrolled in this study
We critically evaluate the emerging evidence demonstrating that MSC Exos are enriched with anti-ferroptotic miRNAs, antioxidant enzymes, and iron homeostasis regulators, which can mitigate cellular ferroptosis
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