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SARS-CoV-2 genetic material is a positive-sense single-stranded RNA and the virus consists of a spherical particle, enveloped, with a diameter of approximately 120 nm ( Rhinolophus affinis ) and pangolin ( Manis javanica ) being most probably the natural and intermediate hosts, respectively ( 2 COVID-19 and Thyroid gland: General concepts Despite being initially described as a respiratory disease, in the course of time it was observed that other organs and systems could be affected by COVID-19, such as cardiovascular system ( Figure 1 )