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Preserving muscle while losing fat is a major therapeutic goal in obesity medicine, as loss of muscle mass can worsen metabolic function and long-term outcomes

Elevated IL-8 levels in PCOS are thus not epiphenomenal but functionally potent, amplifying neutrophil infiltration into adipose and ovarian tissue and facilitating local oxidative and proteolytic damage [25]

This nonapeptide, first isolated from the cerebral venous blood of rabbits during sleep, has been shown to induce slow-wave sleep, modulate pain perception, and exhibit potential antioxidant and immunomodulatory properties