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Immunohistochemistry showed endogenous expression of MGF in the neurogenic regions of the brain and overexpression of MGF increased the number of neural stem cells in these regions

Individuals adhering to vegetarian or vegan eating patterns have heightened vulnerability to B12 insufficiency, potentially experiencing symptoms like chronic tiredness, unpredictable mood fluctuations, and diminished mental clarity

In consequence, lipid peroxidation products regulate multiple signaling cascades implicated in apoptosis and inflammation, such as the NF-B pathway, in which reactive aldehydes activate NF-B by promoting IB degradation and phosphorylation-mediated inactivation of anti-apoptotic Bcl-2, thereby enhancing pro-inflammatory signaling [45]