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Journal of Biological Chemistry 269 , 2375723763 (1994)

GCLC: Glutamate-Cysteine Ligase

La hemoglobina A1c promedio (un indicador clave para el control del azcar en sangre) disminuy un 2,11% en pacientes con diabetes que tomaron la dosis mxima de Mounjaro a largo plazo

Type 2 Diabetes and Metabolic Health Glutathione deficiency is commonly observed in type 2 diabetes, driven by hyperglycemia-induced oxidative stress, impaired cysteine availability, and reduced activity of glutathione synthesis enzymes [2][11]