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[email protected] Copyright 2012 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

A prior late-stage trial published in December showed the drug helped obese or overweight patients with one or more comorbidities, but not type-2 diabetes, lower their weight by 22.7% after 68 weeks, also below the 25% expected

GLP-1 receptor agonists (GLP-1 RAs) are known to act on areas of the brain that control appetite and reward

Likewise, the increase in markers of FAO and ketogenesis in the liver, as well as blood ketone bodies, were not observed in mice co-treated with ATGLi (Fig