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Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei
The studies were done on rodents, the b12 isnt available in the kidneys for very long, weeks, not months it seems.and whether humans with b12 deficiency because of a broken system can access this b12 we wont know without further research
When it comes to vitamin B12 deficiency, people are suggested to take a dosage between 1000 and 2000 mcg per day
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