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In the p53 and apoptosis pathways, G2 arrest stabilization related BCL-XL (phospho-Ser62) protein was increased (FC = 1.24) 22 , pro-apoptotic B-cell lymphoma 2 (BCL2)-associated X protein (BAX

Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

The exact molecular mechanisms and functional consequences of TG2-mediated modification of cellular GSTP1 need to be further investigated