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Acknowledgements We would like to express our sincere gratitude to Professor Zhentao Zhang from the Department of Neurology at Renmin Hospital, Wuhan University, for his invaluable guidance and support throughout this research

Metformin, SLGT-2 inhibitors (examples include empagliflozin, dapagliflozin), GLP-1 receptor agonists (examples include semaglutide, liraglutide), and insulin are generally safe to take with grapefruit

10.1016/j.brainres.2007.02.043 Brain Res

This doesn't mean short-term use failsit means the medication was doing the heavy lifting, and transitioning off requires locked-in dietary and exercise changes to sustain results