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doi: 10.3382/ps/pey423, 149

They sold prescription medications like metformin, which requires a prescription for good reason

This suggests a shared stress or inflammatory response across these conditions, possibly mediated through the hypothalamic-pituitary-adrenal (HPA) axis or other stress-related pathways

Retatrutide is an investigational triple GIP/GLP-1/glucagon receptor agonist and currently provides the strongest clinical support for the glucagon paradox