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The Lancet (2023) This Phase 2 trial evaluated CagriSema versus semaglutide alone and cagrilintide alone in 92 adults with type 2 diabetes and overweight or obesity on metformin with or without an SGLT2 inhibitor across 17 US sites

Rossiello F, Jurk D, Passos JF, dAdda di Fagagna F

The strongest element of dihexa's profile is that its action has been reproduced by groups unconnected to the original discoverers: Siller (2015) dihexa replaced the HGF protein itself in a protocol converting human pluripotent stem cells into hepatocytes

The last step for validating regenerative medicine treatment strategies involves the use of in vivo animal models