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Hyperinsulinaemia also disrupts the balance between FSH and LH, promotes inflammation, and reduces the production of SHBG (the protein that transports sex hormones), leaving too many free oestrogens and androgens circulating in the blood

Quantification of the Contribution of GLP-1 to Mediating Insulinotropic Effects of DPP-4 Inhibition With Vildagliptin in Healthy Subjects and Patients With Type 2 Diabetes Using Exendin [9-39] as a GLP-1 Receptor Antagonist

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