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Of interest, in the group of streptozocin-induced diabetic rats, the treatment with Ex4 reduced inflammation and fibrosis both in the ovary and endometrium, with associated decrease in inflammatory and oxidative stress markers, and increased ovarian reserve

To date, one illness has been reported to the FDA

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Furthermore, in streptozocin (STZ i.c.v) -induced AD rats (77) and APP/PS1 mice (78), DPP-4 inhibitors sitagliptin and saxagliptin were observed to have the ability to eliminate A accumulation, clear abnormal phosphorylation of tau, and improve brain mitochondrial dysfunction probably through activation of AMPK in neuronal cells (66)