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They are becoming a real test of how health systems manage chronic disease at scale

(2018), neurodegeneration-associated molecular patterns (NAMPs) was proposed as endogenous danger signals commonly present in various CNS conditions, which are recognized by a battery of specific receptors constitutively expressed on microglia and trigger their transition into DAM (Figure 3, Table 1), whose primary function is to contain and remove the damage

Naturally secreted oligomers of amyloid protein potently inhibit hippocampal long-term potentiation in vivo

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