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However, some patients report slight differences in how the injection feels, injection site reactions, and post-injection side effect patterns when changing formulations

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Journal of Neuroinflammation Bharat S, et al

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation