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Managing Side Effects Start at the lowest dose and titrate slowly Eat smaller, more frequent meals Avoid high-fat or greasy foods during titration Stay well hydrated Consider timing injections to minimize impact on daily activities Retatrutide vs Tirzepatide: Muscle Loss Concerns Losing muscle along with fat is a real concern with any rapid weight loss

The theme across all of these: protein first, smaller portions, cooked in real fat, and light on refined carbohydrates that add bulk without nutrition

Combination Studies: Explore synergistic effects with other metabolic agents (e.g., insulin, SGLT2 inhibitors) in controlled settings

December 31, 2024