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Senolytic agents include natural compounds such as quercetin 13 or fisetin 14 , -galactosidase-activated nanoparticles and prodrugs 15,16,17 or compounds that target different vulnerabilities of senescent cells, such as HSP90 inhibitors 18 , cardiac glycosides 19,20 or NMT inhibitors 21

Neurotrophic signaling deficiency exacerbates environmental risks for Alzheimers disease pathogenesis

doi: 10.1016/j.msard.2019.02.013 21 BjartmarC.WujekJ

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