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The main mechanisms behind effective glucose regulation are: Glucose-dependent insulin secretion Delayed gastric emptying and increased feeling of fullness (satiety) Suppressed glucagon release GLP-1 has a half-life of a few minutes in vivo as it is cleaved by the dipeptidyl peptidase 4 (DPP-4) enzyme to yield the metabolite GLP-1 (9-36)

A future randomized, double-blind, placebo-controlled trial should study treatment of hyperpigmentation with glutathione using oral dispersible HPC film, with longer-term follow-up and larger sample size