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Or your fizzy cola drink raises your blood sugar quickly, causing energy crashes

JAMA 333 , 113114 (2025)

Disturbances in the intestinal endothelium, lymphoid atrophy, gut dysbiosis, and elevated inflammatory metabolites (TNF, specific pteridines, IL-1, IL-6 and IL-12, fecal calgranulin and myeloperoxidase) further compromise intestinal function [51, 106, 110,111,112] SAM-induced inflammation further inhibits micronutrient uptake, creating a downward spiral in SAM severity and increased morbidity and mortality [104, 113]

Therefore, the risk of serious harm in any given population exposed to primaquine therapy remains largely unknown