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Warning signs include: Persistent right upper quadrant pain lasting more than 6 hours Fever (temperature above 100.4F or 38C) Severe nausea and vomiting Jaundice (yellowing of skin or eyes) Dark urine or pale stools Tenderness when pressing below the right rib cage Patients should also be aware that sudden severe epigastric pain radiating to the back, especially when accompanied by vomiting, may indicate pancreatitis, including gallstone-induced pancreatitis

Only injectable subcutaneous formulations of semaglutide should be used during breastfeeding

In a statement, Scott Brunner, CEO of the Alliance for Pharmacy Compounding, questioned whether the FDA's resolution of the shortage had taken into account demand for the compounded drug and "the number of patients wholl need to be transitioned from a compounded version to a FDA-approved version. "Thats likely hundreds of thousands of patients," Brunner said

GLP-1RAs improve glucose homeostasis, reduce liver fat, and mitigate hepatic inflammation