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It's a signal that the population most likely to seek GLP-1 therapy for cosmetic and metabolic weight goals (rather than diabetes management) may be the population bearing the greatest skeletal cost

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It may also reflect patients increased engagement with healthcare services following GLP-1 RA prescriptions

Comparing Retatrutide to Other Weight Loss Medications Retatrutide's triple-receptor targeting sets it apart from existing weight loss therapies: Semaglutide (Wegovy) : A GLP-1 receptor agonist associated with an average weight loss of approximately 15% after 68 weeks