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49 Further evaluation on a double-blind, randomized phase 1 clinical trial in 98 patients with T2DM on current management with metformin revealed that Danuglipron was generally well tolerated and associated with minimal side effects such as nausea, dyspepsia, and vomiting comparable with the ones observed with the use of injectable GLP-1RA

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A Multicenter, Randomized, Double Blind, Placebo Controlled Phase II Study of PL 14736 Enema in the Treatment of Mild-To-Moderate Ulcerative Colitis

Although the specific mechanism of hemolysis induced by bacterial and viral infection is largely unclear, it has been postulated that phagocytic leukocytes may play a role, through generation of hydrogen peroxide during the phagocytic process (61)