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The role of cystinosin in the intermediary thiol metabolism and redox homeostasis in kidney proximal tubular cells

Kapitza C, Zdravkovic M, Hindsberger C, Flint A

Statistical analysis The mean and standard error (SEM) of each treatment group were calculated for all experiments

Moreover, the redox reaction nanoassembly R-mPDV/PDV/DOX/sil formed by self-assembly of three glutathione responsive polymers can be broken down by GSH-induced cleavage of 3, 3-dithiodipropionic acid (DA) to achieve abrupt drug release and efficient lactate dehydrogenase A (LDHA) silencing thereby inhibiting G-CSF and GM-CSF production and further inhibiting MDSCs recruitment and enhancing anti-tumor immunity (128)