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More serious side effects, though rare, can include Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylactic shock, and liver dysfunction
GPX4 activity depends on GSH and selenium levels, which also affects either the Grx system (GSH-dependent activity of Grxs) or the Trx system (selenium-dependent activity of TrxR)
Preclinical models help researchers ask mechanistic questions, but they do not automatically predict human outcomes
Because vitamin B12 is water-soluble, your body usually just absorbs what it needs and excretes the rest in your urine
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