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Eastward travel (losing hours): If you normally inject at 8 AM on Saturdays and you travel from Los Angeles to New York (3-hour time change), your body experiences Saturday 8 AM Los Angeles time as Saturday 11 AM New York time

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Moreover, one study showed that epithalon improved lipid profile and mean arterial pressure in female patients with hypertension and ischemic heart disease [2]

10.1038/s41598-020-80063-0 186 ZhangX.FuY.LiH.ShenL.ChangQ.PanL.et al (2018)