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The GLP-1 receptor sits on the surface of pancreatic beta cells, neurons in the hypothalamus, cells in the gastrointestinal tract, and several other tissues

doi: 10.3389/fendo.2021.745959 558 Martin-RinconMGelabert-RebatoMGalvan-AlvarezVGallego-SellesAMartinez-CantonMLopez-RiosLet al

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However, the authors concluded that DMH LepR neurons are not essential for satiation or satiety, as the study found no significant increase in food intake or body weight following inhibition or disruption of these neurons [54]