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Zepbound belongs to a class of drugs known as dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonists

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Additionally, the inhibition of GPX4 was thought to accelerate uncontrolled lipid peroxidation, leading to cell death, whereas GPX4 and ACSL4 double knockout cells had significantly prolonged overall survival (Yang et al., 2016)