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If glutathione cannot be recycled, the body becomes overloaded with toxins, leading to an imbalance
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Moreover, it has been observed that the reduced effect of auto-phagocytosis makes RPE cells more susceptible to oxidative stress and that the autophagy system is enhanced to protect RPE cells from oxidative damage [25]
Low basal level of CDNB activity observed in mock HepG2 cells likely resulted from low levels of other GST isoforms, since GSTP1 is not expressed in HepG2 cells (Sison-Young et al., 2015)
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