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Ball told IBJ that Lillys ability to continue making investments in new medications is dependent on the companys being able to enjoy its period of exclusivity and capture revenue from its most popular drugs without competition before generic versions are available

Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy

For further details regarding the methods used, please refer to the Supplementary Materials and Methods

A classic example is paclitaxel, which binds to -tubulin to stabilize microtubulesthis causes G2/M cell cycle arrest and triggers apoptosis (98)