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PIONEER 2-Semaglutida vs empagliflozina, ambas en combinacin con metformina: En un estudio abierto de 52 semanas, se aleatorizaron 822 pacientes con diabetes tipo 2 para ser tratados con 14 mg de semaglutida una vez al da o 25 mg de empagliflozina una vez al da, ambas en combinacin con metformina