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Tirzepatide: available now Tirzepatide is fully FDA-approved and commercially available under two brand names: Mounjaro: Approved for type 2 diabetes management Zepbound: Approved for chronic weight management in adults with obesity (BMI 30+) or overweight (BMI 27+) with at least one weight-related condition Compounded versions of tirzepatide are also available through compounding pharmacies, offering more affordable options for those without insurance coverage

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These findings dont rule out its use, but they do mean close monitoring matters, especially if you already have heart disease or risk factors

for some [dulaglutide (Gerstein et al., 2019), liraglutide (Marso et al., 2016) and semaglutide (Marso et al., 2017)], the CVOTs also confirmed a cardiovascular benefit and eventually led to the approved use of these GLP-1 RAs to reduce cardiovascular risk in people with type 2 diabetes and established CVD or at high cardiovascular risk (Honigberg et al., 2020)