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Specifically, both aerobic training and resistance training lead to a notable rise in the expression of vascular endothelial growth factor (VEGF) and UCP1, enhancing vascularization of the fat tissue, boosting fatty acid oxidation, and increasing the expression of genes linked to the characteristics of brown and beige adipocyte phenotypes such as PGC-1 (Picoli et al., 2020)

Currently, NS-2330 is in Phase II clinical trials for AD and undergoing a Phase II tolerability trial for PD patients with dyskinesia

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Ferroptosis, a novel mode of programmed cell death that relies on the accumulation of iron ions and lipid peroxides, has been shown to be related to several diseases [6, 7]