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ajd Home Scope of Journal Editorial Board Current Issue Past Issues Useful Links Indexing Peer Review Process Special Issue Proposal Published Special Issues Conference Proposal Conference Proceedings ARC Journal of Dermatology Volume-3 Issue-3, 2018, Page No: 1-2 Penile Melanotic Macules: A Case Report Rosa Gimenez-Garcia 1* , Sergio Carrasco Molina 1 Department of Dermatology, Hospital Rio Hortega, Valladolid, Spain

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The combined treatment downregulates the activity of the anti-apoptotic molecule Bcl-2, upregulates the expression of the pro-apoptotic molecules P53 and Bax, and increases the activity of caspases to promote endogenous apoptosis