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Given that glucose variability has been associated with endothelial dysfunction and oxidative stress, both of which contribute to the development and progression of CVD [23,24,25], improving glucose variabilitysomething that cannot be accurately assessed using HbA1c valuesmay represent a novel therapeutic target for managing T2DM

Not all formulations contain enough B12 to fully offset absorption losses, especially at higher semaglutide doses

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