do we have glp 1 in our body GLP-1 for Weight Loss and Diabetes Glucagon-like peptide-1 receptor agonism and

Genetics and molecular research: GMR 15 , doi: 10.4238/gmr.15028644 (2016)

In addition, the GLP-1 can inhibit postprandial gastric emptying and reduce gastric acid secretion, inhibit gastric and duodenal peristalsis by inhibiting vagus nerve, and increase the pressure of pylorus, thus reducing appetite, causing a reduction in body weight and participating in the so-called ileal braking effect (19, 35)

MC5R, exocrine glands MC5R is dominant in sebaceous glands , lacrimal glands, salivary glands and other exocrine organs

Similar to the effects of calycosin, silencing of AIM2 also reversed MSU-induced apoptosis in monocytes and macrophages, indicating that calycosin can suppress apoptosis by deactivating the AIM2 inflammasome via certain pathways, thereby impacting MSU-induced gouty arthritis (79)