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[DOI] [PubMed] [Google Scholar] 127.Zou Y, Wu S, Xu X, Tan X, Yang S, Chen T, Zhang J, Li S, Li W, Wang F

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It works by blocking the NNMT enzyme in fat cells and other tissues, which prevents the conversion of nicotinamide to 1-methylnicotinamide

These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels (Filomeni et al., 2010)