In SURMOUNT-1, at the 15 mg dose over 72 weeks, 91% of participants lost at least 5% of their body weight, 83.5% lost at least 10%, 70.6% lost at least 15%, and 56.7% lost at least 20%
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, has been suggested to exert diverse biological activities involving anti-oxidation, anti-inflammation, and anti-apoptosis ( 2 Research progress of SA in inflammation-related diseases Due to the significant anti-inflammatory, anti-oxidative, and anti-apoptotic effects, SA has been investigated for its potential to treat myocardial ischemia-reperfusion injury, liver injury, respiratory diseases, and other inflammation-related conditions including kidney injury, neuroinflammation, psoriasis, rheumatoid arthritis, and osteoarthritis (Table 1)
We observed similar effects of CR and DL on glucose and insulin tolerance in male 3xTg and NTg mice (Fig