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CJC-1295 also activates direct GH action on skeletal muscle (independent of hepatic IGF-1): skeletal muscle GHR expression (quantifiable by flow cytometry or western blot in human muscle biopsy) drives STAT5b-dependent IGF-1 autocrine synthesis, lipolysis via HSL phosphorylation (GH-direct, IGF-1-independent), and satellite cell GHR-STAT5b activation

Atomic absorption, atomic emission, and flame emission spectrometry