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Physical activity stimulates peristalsis through mechanical vibration, increased blood flow to the gut, and activation of the parasympathetic nervous system

Some users report sleep disruption during the initial weeks of Retatrutide use, which typically resolves as the body adjusts

GIP is another incretin hormone

Patients should be advised to report any suspected adverse reactions via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)