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Pure Appl Chem

Parsad D, Pandhi R, Juneja A

An increasing body of evidence suggests that the KD, owing to its metabolic and biochemical properties, may have therapeutic potential in a range of neurological disorders beyond its established applications [8]

315 Astrocytes in AxD show profound alterations in morphology and function, with evidence of abnormal glutamate clearance, substantial cell stress in the form of upregulated expression of heat shock protein, MAPK pathways, JNK and p38 kinases, as well as increased autophagy and proteasomal activity