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Under oxidative stress, these residues are prone to oxidation in sulfenic acid, which efficiently reacts with GSH leading to form GSSG which is catalytically reduced back to GSH by the NADPH dependent glutathione reductase (GR)

Support for Cardiovascular and Metabolic Health By reducing oxidative stress, glutathione supports healthy blood circulation and balanced metabolic function

Plant Physiol 154:16461658 Jin X, Yang X, Islam E, Liu D, Mahmood Q (2008a) Effects of cadmium on ultrastructure and antioxidative defense system in hyperaccumulator and non-hyperaccumulator ecotypes of Sedum alfredii Hance