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GLP-1, a hormone produced by L cells in the jejunum, ileum, and colon, is released in response to nutrients (DAlessio, 2016)

Wegovy tablets, approved December 22, 2025, sit inside the same prescribing information at 1.5, 4, 9 and 25 mg but carry only the cardiovascular risk reduction and weight reduction indications not the pediatric use and not MASH

This means your cells receive more of what your body truly needsfaster and more effectively

Treating the metabolic conditions becomes part of treating the osteoarthritis. Research has shown that patients with type 2 diabetes are more likely to have severe osteoarthritis as well as a higher likelihood of needing revision surgeries after knee replacements